I would pay money to watch that Primary
One intriguing and rather sci-fi possibility is if biotechnology, or the interaction of technology and the human body and the environment more broadly, becomes a much more salient issue down the road. I could imagine one party becoming much more protectionist and preservationist (anti-globalization, anti-abortion, anti-genetics, pro-union, pro-religion) while the other becomes much more quote-unquote libertarian, no matter what (pro-business, lightly anti-state, pro-genetic manipulation [even in humans], pro-gay rights, globalist, pro-immigration, MOR secularist).
Green Huckabites vs. Dawkinsite Free-traders? How 'bout it?
Someone tell Charles Stross to get to work on it.